Table 2.
Risk of bias assessment.
| Klang et al. | Hamer et al. | Simonnet et al. | Hu et al. | Kalligeros et al. | McMichael et al. | Richardson et al. | Cai et al. | Zheng et al. | Deng et al. | Petrilli et al. | Lighter et al. | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Are the study group at risk of not representing their source populations in a manner that might introduce selection bias? | Unclear | High | Unclear | Low | Low | Unclear | Low | Low | Unclear | Low | Low | Low |
| Was knowledge of the group assignments adequately prevented (i.e., blinded or masked) during the study, potentially leading to the subjective measurement of either exposure or outcome? | Unclear | Unclear | Low | Low | Low | Low | Low | Low | Low | Low | Unclear | Low |
| Were exposure assessment methods lacking accuracy? | Low | Low | Low | Low | Low | Low | Low | Unclear | Low | Low | Low | Low |
| Were outcome assessment methods lacking accuracy? | Low | Low | Low | Low | Low | Low | Low | Unclear | Low | Unclear | Low | Low |
| Was potential confounding inadequately incorporated? | Unclear | Low | Low | Unclear | Low | High | Unclear | Low | Low | Unclear | Unclear | Unclear |
| Were incomplete outcome data inadequately addressed? | Low | Low | Low | Unclear | Low | Low | Low | Low | Low | Unclear | Low | Low |
| Does the study report appear to have selective outcome reporting | Low | Low | Low | Low | Low | Low | Low | Low | Low | Low | Low | Low |
| Did the study receive any support from a company, study author, or other entity having a financial interest in any of the exposures studied? | Low | Low | Low | Low | Low | Unclear | Low | Low | Low | Low | Low | Low |
| Did the study appear to have problems that could put it at risk of bias? | Low | Low | Low | Low | Low | Low | Low | Low | Low | Low | Low | Low |
| Total score (Extra 2 points for peer-reviewed article) | 17 | 17 | 19 | 18 | 20 | 16 | 19 | 18 | 19 | 17 | 16 | 17 |