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. Author manuscript; available in PMC: 2021 Oct 15.
Published in final edited form as: Clin Cancer Res. 2021 Jan 8;27(8):2301–2313. doi: 10.1158/1078-0432.CCR-20-3741

Figure 1: Follicular lymphoma-associated BTK mutations are distributed over the BTK coding region and cluster on the protein surface.

Figure 1:

A: Location of BTK mutations identified by Krysiak et al Blood 2017 and in this study in a linear schema of BTK (22). B: Sanger sequence traces of paired sorted FL B cell (T) and paired CD3 T cell (N) DNA. Mutated residues are indicated by a red arrow. C: Composite 3-D model of BTK with protein domains and location of identified BTK missense mutations.