TABLE 2.
Summary of Lysate, F, Ga, and Gb antibody EIA positivity in RSV PCR+ infants
EIA | Antibody positive in RSV PCR+ infantsa |
|||
---|---|---|---|---|
No+/no tested | Median titer of positive sera | Gp A infection no+/no tested | Gp B infection no+/no tested | |
Lysate | 117/118 | 5661 | 96/97 | 21/21 |
F | 117/118 | 13,403 | 96/97 | 21/21 |
Ga | 88/118 | 1166 | 86/97 | 2/21 |
Gb | 51/118 | 360 | 34/97 | 17/21 |
Ga and Gb | 36/118 | 34/97 | 2/21 | |
Ga or Gb | 103/118 | 86/97 | 17/21 |
Abbreviations: EIA, enzyme-linked immunoassay; PCR, polymerase chain reaction; RSV, respiratory syncytial virus.
These sera from118 PCR+ plus 108 from not PCR+ children were used for a sub study comparison of the RSV group A and B lysate antibody EIA to an RSV F, group RSV A G, and RSV group B G protein EIAs. The results for the RSV PCR+ group show the relative sensitivity for detecting infant infection with each of these EIAs.