Table 3:

Summary of standard mean field model parameters

Parameter	Value
Firing rate of E/I population rE/I
Synaptic activation of E/I population sE/I
Time step in Euler’s method	0.1 ms
Percentage of ACC population receiving a direct S1 input	20%
Excitatory synaptic weights {wEE, wEI}	22
Inhibitory synaptic weights {wII, wIE}	wII = ρwEE
	wIE = ρwEI
Scaling parameter p for inhibitory/excitatory strength	−1.5
Scaling parameter L for long-range projection	0.1
S1/ACC population size ratio κ	2
Gain parameter gS1	2
Gain parameter gACC	3
Scaling parameter for % of pain-responsive neurons $q_{S1}^{+}$, $q_{S1}^{-}$, qI	35%, 14%, 10%
Slope of sigmoid function σE = σI	S1: 0.5; ACC: 0.7
Center of sigmoid function hE = hI	S1: 4; ACC: 3
Synaptic activation time constant for excitatory population τs,E	3 ms
Synaptic activation time constant for inhibitory population τs,I	10 ms
S1 firing time constant for excitatory population τr,E	1 ms
S1 firing time constant for inhibitory population τs,I	3 ms
ACC firing time constant for excitatory population τr,E	3 ms
ACC firing time constant for inhibitory population τs,I	18 ms
Ratio between activation and inactivation times of the synapse γE/I	4
Time delay in S1→ACC projection: ΔS1	20 ms
Time delay: Δx	75 ms