Table 2.
Pupillary light reflex responses in patients with Fabry disease and healthy control subjects.
| Controls (n = 14) | Fabry disease (n = 14) | P value | Adjusted P valuec | |
|---|---|---|---|---|
| Initial pupil diameter (mm) | 5.64 ± 0.61 | 5.16 ± 0.77 | 0.077a | 0.154 |
| Amplitude of contraction (mm) | 1.86 ± 0.18 | 1.64 ± 0.26 | 0.018a | 0.048 |
| Latency of contraction (ms) | 274.5 (250.5–279.8) | 253.5 (188.8–278.0) | 0.285b | 0.326 |
| Duration of contraction (ms) | 659.5 ± 93.0 | 577.1 ± 69.0 | 0.013a | 0.048 |
| Velocity of contraction (mm/s) | 5.98 ± 0.63 | 5.59 ± 1.03 | 0.238a | 0.326 |
| Latency of dilation (ms) | 915.5 (855.3–1005.0) | 819.0 (770.5–868.0) | 0.012b | 0.048 |
| Duration of dilation (ms) | 1571.5 (1485.5–1637.3) | 1633.0 (1571.5–1708.0) | 0.265b | 0.326 |
| Velocity of dilation (mm/s) | 1.81 ± 0.36 | 1.87 ± 0.41 | 0.688a | 0.688 |
Data are expressed as mean ± SD for parametric variables and median (IQR) for non-parametric variables.
The bold P values represent statistically significant differences.
aIndependent samples t-test.
bMann Whitney U-test.
cP values were adjusted using a Benjamini–Hochberg false discovery rate (FDR) correction procedure.