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. 2021 Apr 14;11:8163. doi: 10.1038/s41598-021-87097-y

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© The Author(s) 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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CCG RNA duplexes that contain 1 to 4 C…C mismatches are quite stable. (A) Time vs. RMSD profile showing less conformational changes in the RNA duplexes that contain one to four C…C mismatches. This figure was plotted by using MATLAB 7.11.0 software (www.mathworks.com). Cartoon representation of the snapshots corresponding to (B) RC4 (4 C…C mismatches), (C) RC3 (3 C…C mismatches), (D) RC2 (2 C…C mismatches) and (E) RC1 (1 C…C mismatch). Orange colored base pairs represent C…C mismatches (B–E). This figure was generated by using pymol 1.3 (www.pymol.com).