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. 2021 Apr 14;11:8195. doi: 10.1038/s41598-021-87499-y

Table 1.

Characteristics of the sample population.

Control (n = 71,076) DM (n = 35,538) P a
n % n %
Age, years (mean ± SD) 51.06 ± 11.01 51.07 ± 11.00 0.926
0–9 84 0.12 41 0.12 0.998
10–19 275 0.39 133 0.37
20–29 1907 2.68 946 2.66
30–39 7907 11.12 3931 11.06
40–49 21,672 30.49 10,879 30.61
50–59 26,274 36.97 13,094 36.85
60–69 9852 13.86 4967 13.98
≥ 70 3105 4.37 1547 4.35
Sex
Female 28,044 39.46 14,022 39.46 1.000
Male 43,032 60.54 21,516 60.54
Charlson’s comorbidity index
0 40,043 56.34 16,130 45.39 < 0.001
1 16,769 23.59 9346 26.30
2–3 7840 11.03 5267 14.82
≥ 4 6424 9.04 4795 13.49
Comorbidities
HF 1187 1.67 1237 3.48 < 0.001
AMI 316 0.44 325 0.91 < 0.001
Stroke 3482 4.90 2804 7.89 < 0.001
Ischemic heart disease 6684 9.40 5687 16.00 < 0.001
Angina 2469 3.47 2018 5.68 < 0.001
Peripheral vascular disease 2184 3.07 1666 4.69 < 0.001
Hypertension 14,166 19.93 14,902 41.93 < 0.001
Hyperlipidemia 9553 13.44 9543 26.85 < 0.001
Renal failure 2935 4.13 2299 6.47 < 0.001
Chronic liver disease 11,892 16.73 9597 27.00 < 0.001
COPD 8610 12.11 5264 14.81 < 0.001
Cataract 10,260 14.44 9219 25.94 < 0.001
Level of urbanization
Urban 56,117 78.95 27,760 78.11 0.002
Suburban 11,126 15.65 5711 16.07
Rural 3833 5.39 2067 5.82
Monthly income (NT$)
0 2761 3.88 1481 4.17 < 0.001
1–21,000 14,455 20.34 8048 22.65
21,000–33,300 22,092 31.08 11,838 33.31
 ≥ 33,301 31,768 44.70 14,171 39.88
Residence
North 40,662 57.21 19,240 54.14 < 0.001
Central 14,146 19.90 7543 21.23
South 14,911 20.98 7952 22.38
East and other 1357 1.91 803 2.26
New-onset myopia
Low myopia 1189 1.67 898 2.53 < 0.001
High myopia 193 0.27 97 0.27 0.967
Low/high myopia/astigmatism 1419 2.00 1058 2.98 < 0.001

aCategorical variables: Chi-squared test; continuous variables: T test.