Table 3.
Symptomatic COVID-19 | Asymptomatic COVID-19 | ||||
---|---|---|---|---|---|
Items | With pneumonia | Without pneumonia | With pneumonia | Without pneumonia | p-value |
(n = 430) | (n = 31) | (n = 23) | (n = 14) | ||
Treatments | |||||
Antiviral therapy | 420 (97.7) | 31 (100) | 23 (100) | 13 (92.9) | 0.865 |
Abidol | 200 (46.5) | 16 (51.6) | 14 (60.9) | 6 (42.9) | 0.543 |
Lopinavir/ritonavir | 310 (72.1) | 24 (77.4) | 10 (43.5)* | 8 (57.1) | 0.022 |
Interferon | 259 (60.2) | 24 (77.4) | 14 (60.9) | 8 (57.1) | 0.295 |
Ribavirin | 44 (10.2) | 2 (6.5) | 2 (8.7) | 1 (7.1) | 0.876 |
Chloroquine phosphate | 53 (12.3) | 2 (6.5) | 4 (17.4) | 2 (14.3) | 0.635 |
Antibiotic therapy | 233 (54.2)* | 11 (35.5) | 7 (30.4)* | 3 (21.4)* | 0.004 |
Administration of corticosteroids | 124 (28.8)* | 2 (6.5)* | 0 (0)* | 0 (0)* | <0.001 |
Non-invasive mechanical ventilation | 18 (4.2) | 0 (0) | 0 (0) | 0 (0) | 0.121 |
Invasive mechanical ventilation | 11 (2.6) | 0 (0) | 0 (0) | 0 (0) | 0.229 |
ECMO | 7 (1.6) | 0 (0) | 0 (0) | 0 (0) | 0.339 |
CRRT | 9 (2.1) | 0 (0) | 0 (0) | 0 (0) | 0.278 |
Clinical outcomes | |||||
Severe cases | 61 (14.2)* | 3 (9.7) | 0 (0) | 0 (0) | 0.011 |
Critical cases (admission to ICU) | 46 (10.7)* | 1 (3.2) | 0 (0) | 0 (0) | 0.019 |
ARDS | 18 (4.2) | 0 (0) | 0 (0) | 0 (0) | 0.121 |
Death | 3 (0.7) | 0 | 0 | 0 | 0.533 |
Duration of viral shedding, days | 14.0 (9.0–21.0) | 15.0 (8.8–23.8) | 13.0 (7.0–19.0) | 13.0 (8.3–17.8) | 0.524 |
Duration of hospitalization, days | 16.0 (11.5–24.0) | 16.0 (10.0–23.0) | 16.0 (11.0–22.0) | 12.0 (8.8–17.0)* | 0.234 |
Values are presented as median (IQR) or number (percentage).
p < 0.05 compared with other groups combined; p-values were compared by Kruskal–Wallis test, χ2 test, Fisher exact test, or one-way analysis of variance.
ECMO, extracorporeal membrane oxygenation; CRRT, continuous renal replacement therapy; ARDS, acute respiratory distress syndrome; ICU, intensive care unit.