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. 2021 Apr 14;11:8152. doi: 10.1038/s41598-021-87507-1

Table 3.

Grades of recommendation, assessment, development and evaluation approach summarizing the evidence.

Certainty assessment No of patients Effect Certainty Importance
No. of studies Study design Risk of bias Inconsistency Indirectness Imprecision Other considerations Extra-short implants (≤ 6 mm) Longer implants (≥ 8 mm) Relative (95% CI) Absolute (95% CI)
Survival rate (implant level) (follow up: range 1 years to 5 years)
22 Randomised trials Not serious Not serious Not serious Seriousa None 1193/1243 (96.0%) 1290/1333 (96.8%) RR 0.991 (0.974 to 1.009) 9 fewer per 1000 (from 25 fewer to 9 more)

⨁⨁⨁◯

Moderate

Critical
MBL (measured from IP) (follow up: range 1 years to 5 years)
19 Randomised trials Not serious Seriousb Not serious Serious None 962 953 MD 0.22 mm lower (0.277 lower to 0.164 lower)

⨁⨁◯◯

Low

Critical
MBL (measured from PR) (follow up: range 1 years to 5 years)
13 Randomised trials Not serious Not serious Not serious Serious None 404 485 MD 0.016 mm higher (0.036 lower to 0.068 higher)

⨁⨁⨁◯

Moderate

critical
Biological complications rate (follow up: range 1 years to 5 years)
14 Randomised trials Not serious Seriousc Not serious Not serious None 50/460 (10.9%) 161/520 (31.0%) RR 0.321 (0.243 to 0.422) 210 fewer per 1000 (from 234 to 179 fewer)

⨁⨁⨁◯

Moderate

Important
Prosthesis complications rate (follow up: range 1 years to 5 years)
12 Randomised trials Not serious Not serious Not serious Seriousd None 53/386 (13.7%) 48/379 (12.7%) RR 1.092 (0.777 to 1.535) 12 more per 1000 (from 28 fewer to 68 more)

⨁⨁⨁◯

Moderate

Important
Survival rate (patient level) (follow up: range 1 years to 5 years)
18 Randomised trials Not serious Not serious Not serious Seriousd None 514/566 (90.8%) 592/632 (93.7%) RR 0.970 (0.938 to 1.003) 28 fewer per 1000 (from 58 fewer to 3 more)

⨁⨁⨁◯

Moderate

Critical

Question: Extra-short implants (≤ 6 mm) compared to longer implants (≥ 8 mm) for partially or totally edentulous patients.

GRADE Working Group grades of evidence. High certainty: We are very confident that the true effect lies close to that of the estimate of the effect. Moderate certainty: We are moderately confident in the effect estimate: The true effect is likely to be close to the estimate of the effect, but there is a possibility that it is substantially different. Low certainty: Our confidence in the effect estimate is limited: The true effect may be substantially different from the estimate of the effect. Very low certainty: We have very little confidence in the effect estimate: The true effect is likely to be substantially different from the estimate of effect. Generated by GRADEpro GDT web application, http://gradepro.org.

CI: confidence interval; RR: risk ratio; MD: mean difference.

aSmall simple size (less than OIS), CI of RR included 1.

bHeterogeneity across the studies, I2 = 58.10%, CI for I2 = 30.3% to 74.8%.

cHeterogeneity across the studies, I2 = 48.8%, CI for I2 = 5.1% to 72.39%.

dSmall simple size (less than OIS), CI of RR included 1.