Figure 6.

Ginkgetin blocks DiI-oxLDL uptake in macrophages. Macrophages were pretreated with vehicle or two doses of ginkgetin (1 or 10 µM) for 3 h followed by incubation with DiI-labeled oxLDL (2.5 µg/mL) for 30 min at 37 °C. (A) Representative images of DiI-oxLDL from ten different fields per condition (original magnification, 40×) are shown. DiI-oxLDL uptake indicated by red fluorescence. (B) Bar graphs show mean DiI fluorescence intensity (mean ± SEM) analyzed using NIH ImageJ software. **p < 0.01 for oxLDL uptake in untreated versus ginkgetin treated cells; n = 50 cells/condition.