Table 3.

Between-group differences of cortical thickness across orthostatic hypotension.

Cortical areas		no-OH (n = 36)	Delayed OH (n = 25)	Classical OH (n = 21)	Test statistics (F)	P-value	Post hoc analysis	P for linear trend
Frontal	Mean ± SEM	3.17 ± 0.02	3.14 ± 0.02	3.05 ± 0.02	7.96	0.001	a > c***, b > c*	<0.001
Right	Mean ± SEM	3.18 ± 0.02	3.15 ± 0.02	3.06 ± 0.03	7.49	0.001	a > c***, b > c*	<0.001
Left	Mean ± SEM	3.16 ± 0.02	3.12 ± 0.02	3.05 ± 0.02	7.00	0.002	a > c**	<0.001
Parietal	Mean ± SEM	2.98 ± 0.03	2.88 ± 0.04	2.79 ± 0.05	5.37	0.007	a > c**	0.002
Right	Mean ± SEM	2.96 ± 0.03	2.88 ± 0.04	2.79 ± 0.05	4.68	0.012	a > c**	0.004
Left	Mean ± SEM	3.00 ± 0.04	2.88 ± 0.05	2.80 ± 0.05	5.11	0.008	a > c**	0.003
Temporal	Mean ± SEM	3.50 ± 0.03	3.44 ± 0.03	3.38 ± 0.04	3.09	0.051	–	0.018
Right	Mean ± SEM	3.55 ± 0.03	3.49 ± 0.04	3.41 ± 0.04	3.76	0.028	a > c*	0.008
Left	Mean ± SEM	3.43 ± 0.03	3.38 ± 0.03	3.35 ± 0.04	1.76	0.179	–	0.079
Occipital	Mean ± SEM	3.38 ± 0.04	3.26 ± 0.05	3.26 ± 0.05	2.62	0.079	–	0.072
Right	Mean ± SEM	3.47 ± 0.05	3.29 ± 0.06	3.32 ± 0.06	3.21	0.046	–	0.074
Left	Mean ± SEM	3.30 ± 0.04	3.23 ± 0.05	3.20 ± 0.05	1.18	0.313	–	0.168
Whole	Mean ± SEM	3.27 ± 0.02	3.22 ± 0.02	3.15 ± 0.03	6.62	0.002	a > c**	0.001
Right	Mean ± SEM	3.31 ± 0.02	3.25 ± 0.03	3.17 ± 0.03	6.61	0.002	a > c**	0.001
Left	Mean ± SEM	3.24 ± 0.02	3.19 ± 0.02	3.13 ± 0.03	5.24	0.007	a > c**	0.002

Analysis of covariance, adjusted for age, sex, disease duration, and Mini-Mental Status Examination, was applied to compare between-group differences. Pairwise multiple comparisons were adjusted by Tukey’s HSD. Polynomial contrasts were performed, when appropriate, to appreciate the linear trend.

OH orthostatic hypotension, SEM standard error of the mean.

*p-value < 0.05, **p-value < 0.01, ***p-value < 0.001.

^ano-OH, ^bDelayed OH, ^cClassical OH.