Figure 1.
Comparisons of lung wet (A) and dry (B) weight and wet/dry weight ratio (W/D) of the lung (C) between control group (Ctrl), group exposed to paraquat aerosol at doses of 54 mg/m3 (PQ-54 mg/m3), groups exposed to PQ-54 mg/m3 and treated with 5 and 10 mg/kg/day pioglitazone (Pio-5 mg/kg/day and Pio-10 mg/kg/day), 20 and 80 mg/kg/day carvacrol (C-20 mg/kg/day and C-80 mg/kg/day), 0.03 mg/kg/day dexamethasone (Dexa-0.03 mg/kg/day) and 5 mg/kg/day pioglitazone + 20 mg/kg/day carvacrol (Pio-5 mg/kg + C-20 mg/kg). +p < 0.05 compared to the PQ-54 mg/m3, #p < 0.05 compared to dexamethasone, £p < 0.0 comparisons between Pio-5 with Pio-5 mg/kg/day + C-20 mg/kg/day group. Data are presented as mean ± SEM (n = 6 in each group). Comparisons between different groups were made using one-way ANOVA followed by Tukey’s multiple comparison test.