TABLE 1.
A |
B |
C |
D |
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F0-Saline_F1 Saline |
F0-Saline_F1 HDM |
F0-HDM_F1-Saline |
F0-HDM_ F1 = HDM |
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Gene | Mean | SEM | Mean | SEM | p value (B vs. A) | Mean | SEM | p value (C vs. A) | Mean | SEM | p value (D vs. C) | p value (D vs. B) |
Ccnd1 | 1.838 | 0.708 | 26.169 | 4.708 | 0.039 | 1.339 | 0.206 | 0.899 | 28.630 | 4.786 | 0.072 | 0.981 |
Pcna | 0.353 | 0.040 | 4.483 | 0.949 | 0.065 | 1.896 | 0.592 | 0.279 | 5.225 | 0.509 | 0.045 | 0.897 |
Col1a | 0.285 | 0.092 | 0.486 | 0.121 | 0.587 | 0.346 | 0.036 | 0.919 | 0.666 | 0.027 | 0.009 | 0.545 |
Col3a | 0.638 | 0.178 | 1.087 | 0.127 | 0.310 | 1.071 | 0.251 | 0.563 | 2.003 | 0.187 | 0.136 | 0.056 |
Muc5b | 1.168 | 0.118 | 1.053 | 0.108 | 0.885 | 1.156 | 0.120 | 1.000 | 1.276 | 0.175 | 0.937 | 0.719 |
Sma | 0.347 | 0.043 | 0.443 | 0.103 | 0.824 | 0.422 | 0.166 | 0.967 | 0.806 | 0.114 | 0.363 | 0.212 |
Camk2d | 3.537 | 0.309 | 7.137 | 0.544 | 0.011 | 3.387 | 0.137 | 0.966 | 8.666 | 0.979 | 0.077 | 0.587 |
Mylk | 1.146 | 0.187 | 1.230 | 0.043 | 0.967 | 0.989 | 0.160 | 0.914 | 1.164 | 0.094 | 0.787 | 0.913 |
mRNA levels measured via RTPCR. The 2∧(−ΔΔCt) method was used to calculate the relative expression level of transcripts normalized to Rpl19. P values derived from Ordinary One-Way ANOVA with Tukey’s test for multiple comparisons. Significant P values are in bold.