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Multivariate analyses of prognostic factors for PFS.
| Prognosticators | P-value |
|---|---|
| Performance status | 0.371 |
| LDH | 0.107 |
| Liver metastases | 0.533 |
| Regimen | 0.166 |
| TrHE | 0.014 |
LDH, lactate dehydrogenase; Regimen, including BRAFi, BRAFi+MEKi and BRAFi+anti-PD-1 antibody; trHE, treatment-related hepatotoxicity defined as the increase of either ALT, AST or bilirubin levels.
