Table 4.
Results of the sensitivity analysis (open-label studies).
| Outcome | Random model | Omitted large sample study | Omitted small sample study | ||||||
|---|---|---|---|---|---|---|---|---|---|
| PE | 95% CI | P-value | PE | 95% CI | P-value | PE | 95% CI | P-value | |
| Respond rate | 0.56 | 0.43, 0.69 | <0.0001* | 0.59 | 0.48, 0.71 | 0.001* | 0.55 | 0.42,0.69 | <0.0001* |
| Remission rate | 0.35 | 0.27, 0.44 | 0.127 | 0.37 | 0.28, 0.46 | 0.215 | 0.36 | 0.27. 0.45 | 0.225 |
| Recurrence rate | 0.14 | 0.04, 0.25 | 0.383 | 0.21 | 0.04, 0.38 | 0.347 | 0.13 | 0.02, 0.23 | 0.503 |
| AEs rate | 0.89 | 0.85, 0.93 | <0.0001* | 0.90 | 0.86, 0.94 | <0.0001* | 0.81 | 0.76, 0.87 | <0.0001* |
PE, Pooled Estimate; 95% CI, 95% confidence intervals;
significant difference.