Table 3.

Representative software tools predicting Tat substrates in Gram-negative bacteria.

Tool	Method	Target	URL or reference
TATFIND 1.4	Regular expression pattern; Hydrophobicity analysis	Tat/SPI; Sec/SPI	http://signalfind.org/tatfind.html; [33], [34]
TatP 1.0	Regular expression pattern; ANN	Tat/SPI; Sec/SPI; Cleavage site	https://services.healthtech.dtu.dk/service.php?TatP-1.0; [35]
PRED-TAT	HMM	Tat/SPI; Sec/SPI; Cleavage site	http://www.compgen.org/tools/PRED-TAT; [36]
SignalP5	DNN	Tat/SPI; Sec/SPI; Sec/SPII; Cleavage site	https://services.healthtech.dtu.dk/service.php?SignalP-5.0; [14]