TABLE 2.
The enriched KEGG pathways associated with the pDC in TCGA.
ID | Description | Set size | NES | p value | Group |
hsa04662 | B cell receptor signaling pathway | 74 | 1.961 | 0.001 | pDChigh |
hsa04062 | Chemokine signaling pathway | 158 | 2.404 | 0.001 | pDChigh |
hsa04650 | Natural killer cell-mediated cytotoxicity | 86 | 2.08 | 0.001 | pDChigh |
hsa05235 | PD-L1 expression and PD-1 checkpoint pathway in cancer | 76 | 1.688 | 0.001 | pDChigh |
hsa04660 | T cell receptor signaling pathway | 90 | 2.048 | 0.001 | pDChigh |
hsa04668 | TNF signaling pathway | 101 | 1.893 | 0.001 | pDChigh |
hsa01200 | Carbon metabolism | 92 | −1.659 | 0.003 | pDClow |
hsa04110 | Cell cycle | 121 | −2.587 | 0.004 | pDClow |
hsa04218 | Cellular senescence | 143 | −1.639 | 0.004 | pDClow |
hsa00562 | Inositol phosphate metabolism | 70 | −1.637 | 0.007 | pDClow |
hsa05211 | Renal cell carcinoma | 62 | −1.531 | 0.016 | pDClow |
hsa03018 | RNA degradation | 67 | −1.818 | 0.003 | pDClow |