Table 1:
Trait | Overall | Fatal N = 256 | Non-fatal N = 745 | P value |
---|---|---|---|---|
Age | 58.4 ± 10.6 | 60.9 ± 10.5 | 57.5 ± 10.5 | < 0.001 |
Year of HCC diagnosis | 2012 (2009–2013) | 2010 (2008–2013) | 2012 (2010–2014) | < 0.001 |
% Male | 67.6% | 70.7% | 66.6% | < 0.001 |
Race | ||||
Asian | 6.6% | 3.9% | 7.5% | 0.057 |
Black | 7.4% | 9.8% | 6.6% | |
Hispanic | 17.9% | 15.2% | 18.8% | |
White | 61.2% | 65.4% | 59.9% | |
Other/unknown | 6.9% | 5.9% | 7.2% | |
Subspecialty care before cancer diagnosis | ||||
Gastroenterologist | 89.7% | 91.0% | 89.3% | 0.41 |
Hepatology (subset of gastroenterologists) | 29.3% | 23.1% | 31.4% | 0.011 |
Number of imaging studies before cancer diagnosis | ||||
Ultrasound | 2 (1–4) | 2 (1–4) | 2 (1–5) | 0.88 |
Computed tomography | 1 (0–3) | 2 (1–3) | 1 (0–2) | 0.004 |
Magnetic resonance imaging | 0 (0–2) | 0 (0–1) | 0 (0–2) | 0.006 |
Computed tomography or magnetic resonance imaging | 2 (1–4) | 2 (1–4) | 2 (1–4) | 0.57 |
Any imaging | 5 (3–9) | 5 (3–8) | 5 (2–9) | 0.84 |
Region | ||||
Mountain | 4.0% | 4.7% | 3.8% | 0.003 |
Midwest | 16.5% | 19.9% | 15.3% | |
Northeast | 7.1% | 8.2% | 6.7% | |
Pacific | 17.8% | 9.8% | 20.5% | |
Southeast | 34.2% | 38.3% | 32.8% | |
Southwest | 20.5% | 19.1% | 20.9% | |
Hepatitis C virus | 67.3% | 64.1% | 68.5% | 0.20 |
Hepatitis B virus | 14.3% | 9.8% | 15.8% | 0.017 |
Alcohol history | 59.0% | 69.9% | 55.3% | < 0.001 |
Complications at cirrhosis diagnosis | ||||
Ascites | 6.7% | 4.7% | 7.4% | 0.10 |
Encephalopathy | 2.7% | 3.5% | 2.4% | 0.39 |
Variceal bleed | 8.3% | 8.6% | 8.2% | 0.84 |
Any decompensation | 15.4% | 15.2% | 15.4% | 0.94 |
Alpha-fetoprotein measurement | 62.3% | 52.9% | 65.5% | < 0.001 |