Table 2.

Evaluation of SARS-CoV-2 transmission between ferrets.

References	Infected ferrets	Transmission method	Challenged naïve ferrets
Kim et al. (2020)	- All ferrets inoculated with SARS-CoV-2 developed fever at 2–8 days post-infection	Direct contact with other infected ferrets	- All became febrile with reduced activity 4–6 days post-contact - Most collected specimens were positive for viral RNA - Isolation of viruses from nasal washes
		Indirectly via aerosols → Different cages with a permeable partition	- None of the ferrets developed fever - Detection of viral RNA in nasal washes from only 2 of 6 ferrets with indirect contact - Positive serological titer (16) in only one
Schlottau et al. (2020)	- Infection of 12 ferrets intranasally with 105 TCID50 of viral load - None developed fever or body weight loss. - Detection of virus in nasal washes in most animals by qPCR between 2 and 8 days post-infection and culture at 2–4 days post-infection - All developed neutralizing antibodies	Direct contact with other infected ferrets	- All three naive ferrets acquired SARS-CoV-2 with viral RNA detection in nasal washes over 8–21 days post-infection - Detection of neutralizing antibodies in only one contact ferret
Richard et al. (2020)	- Infection was confirmed by viral RNA shedding in nasal washes from 3 to 19 days post-infection	Direct contact with other infected ferrets	- Transmission to four of four naïve animals after 1–3 days. - Detection of viral RNA in newly infected ferrets up to 13–15 days post-infection
		Indirect transmission → Close but different cages	- Transmission to three of four naïve animals - Viral RNA was detected from 3 to 7 days post-exposure and over 13–19 days - Lower neutralizing antibody titers