Table 2.
Increased DNA repair and miRNAs in OC.
| miRNAs | Cell/Tissue | Chemotherapy | Target mRNA | Response to treatment | References |
|---|---|---|---|---|---|
| miR-211 | Tissue | Platinum | DDR | ↑ | (29) |
| NER | |||||
| miR-30a-3p | A2780, IGROV1 | Cisplatin | ERCC1, ATP7A | ↑ | (30) |
| HR | |||||
| miR-9 | Tissue | Cisplatin | BRCA1 | ↑ | (31) |
| miR-506 | OVCA433, SKOV3, HeyA8 | Cisplatin | RAD51 | ↑ | (32) |
| miR-216b | SKOV3 | Cisplatin | PARP1 | ↑ | (33) |
| TLS | |||||
| miR-96 | U2OS, HeLa, HCC1937, MDA-MB-231 | Cisplatin | REV1, RAD51 | ↑ | (34) |
| miR-93 | SKOV3 | Cisplatin | Pol η | ↑ | (35) |