Table 4. Liver stiffness value and ICGR15 for preoperative risk assessment of PHLF.
| Parameter | AUC | Cut-off value | Sensitivity (%) | Specificity (%) | Likelihood ratio | P value |
|---|---|---|---|---|---|---|
| ≥ PHLF A (n=129 vs. n=43) | ||||||
| LSV | 0.624 (0.536–0.712) | 8.45 kPa | 86.1 (72.1–94.7) | 40.3 (31.8–49.3) | 1.44 | 0.015 |
| ICGR15 | 0.631 (0.542–0.721) | 2.95% | 90.7 (77.9–97.4) | 31.0 (23.2–39.8) | 1.31 | 0.01 |
| ≥ PHLF B (n=153 vs. n=19) | ||||||
| LSV | 0.699 (0.576–0.821) | 12.70 kPa | 68.4 (43.5–87.4) | 71.2 (63.4–78.3) | 2.38 | 0.005 |
| ICGR15 | 0.570 (0.436–0.704) | 5.70% | 52.6 (28.9–75.6) | 63.4 (55.2–71.0) | 1.44 | 0.32 |
| ≥ PHLF C (n=167 vs. n=5) | ||||||
| LSV | 0.831 (0.737–0.925) | 14.90 kPa | 80.0 (28.4–99.5) | 80.2 (73.4–86.0) | 4.05 | 0.01 |
| ICGR15 | 0.717 (0.515–0.920) | 6.45% | 80.0 (28.4–99.5) | 71.9 (64.4–78.9) | 2.84 | 0.098 |
Data in parentheses are 95% confidence intervals. PHLF, post-hepatectomy liver failure; ICGR15, indocyanine green retention rate at 15 minutes; LSV, liver stiffness value; AUC, area under the receiver operating characteristic curve.