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. 2021 May;11(5):2169–2186. doi: 10.21037/qims-20-845

Figure 2.

Figure 2

In vivo PAI of brain tumor. (A) PAI of tumor vessels prior to, 1 min after, and 48 h after laser irradiation. Red arrow denotes vascular tortuosity (56), Scale bar: 100 µm; (B) PAI of brain tumor region before, and after 24 h, of injection of nanoparticles showing blood vessels (gray) and brain tumor (green tumor) (57); (C) Representative PAI of brain tumor region before, and 12 h after, tail vein injection of contrast agents showing blood vessels (532 nm, red) and the nanoparticles accumulate in the brain tumor tissue (680 nm, green) (58); (D) In vivo PAI of tumor-bearing mice at a different time points after intravenous injection of nanoparticles (59). PAI, photoacoustic imaging.