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. 2021 Apr 1;12:560738. doi: 10.3389/fphys.2021.560738

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Copyright © 2021 Wang, Zhao, Shi, Niu, Liu and Chen.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Confocal micrographs of apoptotic interstitial cells of Cajal (ICC) labeled with c-kit (green), TUNEL (red), and DAPI (blue). (A) In the control group, many c-kit + cells were observed in the gastric wall, but a few of c-kit + /TUNEL + cells were found. The number of ICC was decreased in the DM and diabetic and sham EA (DM + SEA) group. A few apoptotic ICC was seen in the DM + LEA and DM + HEA groups. Scale bars = 20 mm. (B) Quantification of c-kit + /TUNEL + cells in the stomach of each group. One-way ANOVA was used to analyze the data, and the Dunnett T3 post hoc test was used for the analyses. *P < 0.05 compared with the DM group.