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. 2021 Apr 1;11:616058. doi: 10.3389/fonc.2021.616058

Figure 2.

Figure 2

(A) Under third-line systemic chemotherapy, progressive solitary, surgically unresectable colorectal liver metastasis on the border between segment IVa and VIII. (B) The lesion has been initially transarterially chemoembolized with DEB-IRI (Irinotecan-loaded drug-eluting beads). (C) contrast-enhanced MRI shows subtotal devascularisation of the metastasis with a still vital tumour margin on the right lateral-apical side. (D) The marginal recurrences have been interstitially brachytherapied in the interval. The topogram clearly shows the parallel positioning of the applicators. (E) Excellent local tumor control was observed after 3 months. (F) timely shrinkage of the metastasis as well as further local tumor control without detection of recurrence after 6 months. (G) Local tumor control also confirmed after 12 months by the absence of diffusion restriction in DWI. (H) The corresponding ADC-maps.