Table 3.

Univariate and multivariate Cox regression analyses of clinicopathologic factors for overall survival in HCC from the TCGA database.

Items	Training cohort				Validation cohort				Total cohort
	Univariate Cox		Multivariate Cox		Univariate Cox		Multivariate Cox		Univariate Cox		Multivariate Cox
	HR	P	HR	P	HR	P	HR	P	HR	P	HR	P
Gender	1.313	0.315			1.319	0.269			1.260	0.201
Age	1.015	0.125			1.012	0.245			1.012	0.091
Child grade	1.335	0.619			1.768	0.141			1.543	0.157
BMI	0.963	0.145			1.027	0.123			1.000	0.998
Histologic grade	1.041	0.834			1.276	0.158			1.104	0.410
pT	2.091	0.000	2.809	0.127	1.358	0.020	1.227	0.662	1.683	0.000	1.655	0.213
pN	4.473	0.144			1.274	0.811			2.029	0.324
pM	–	–			4.190	0.017	2.777	0.151	4.077	0.017	2.131	0.254
Tumor stage	2.158	0.000	0.612	0.495	1.363	0.015	1.019	0.968	1.638	0.000	0.955	0.913
Risk score	6.681	0.000	4.544	0.000	2.390	0.003	2.106	0.031	3.941	0.000	3.218	0.000

Bold values are statistically significant.