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. 2021 Apr 15;101(7):851–864. doi: 10.1038/s41374-021-00593-7

Fig. 1. 5-HT causes vascular hyperpermeability in the airways and upper GI tract.

Fig. 1

Vascular hyperpermeability was assessed by the presence of Evans Blue in tissues of the airways, esophagus, and stomach following the intravenous injection of increasing concentrations of 5-HT (30–1000 µg/kg). Data are expressed as mean ± S.E.M., n = 6–9 mice per group. *p < 0.05; **p < 0.01; ***p < 0.001; ****p < 0.0001; significantly different compared to vehicle treatment (1% DMSO in 0.9% saline); one-way ANOVA and Dunnett’s multiple comparisons test.