Table 1.
|
Naive
|
PCL
|
Cyan-10
|
Cyan-15
|
Cyan-20
|
GSTP +ve foci % area | 0.09 ± 0.07 | 47.2 ± 12.4a | 33.4 ± 11.4b | 8.95 ± 4.29b,c | 3.83 ± 2.45b,c |
PCNA | +++ | ++ | + | + |
Values are mean ± SD; number of animals = 6 rats/each group. Examined field; 10 fields/liver section.
P < 0.05 significant differences compared to naïve group.
P < 0.05 significant differences compared to precancerous lesion group.
P < 0.05 significant compared to cyanidin-3-O-glucoside-10, One-way ANOVA followed by Tukey’s test. +: Positive expression found in 1-3 fields; ++: Positive expression found in 4-6 fields; +++: Positive expression found in 7-10 field; PCL: Precancerous lesion; Cyan: Cyanidin-3-O-glucoside; GSTP: Glutathione S-transferase placental; PCNA: Proliferating cell nuclear antigen.