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. 2021 Apr 14;27(14):1435–1450. doi: 10.3748/wjg.v27.i14.1435

Table 1.

Expression rate of hepatocytes positive for glutathione S-transferase placental and proliferating cell nuclear antigen were calculated as number of positive field expression in 10 fields per rat liver tissue


Naive
PCL
Cyan-10
Cyan-15
Cyan-20
GSTP +ve foci % area 0.09 ± 0.07 47.2 ± 12.4a 33.4 ± 11.4b 8.95 ± 4.29b,c 3.83 ± 2.45b,c
PCNA +++ ++ + +

Values are mean ± SD; number of animals = 6 rats/each group. Examined field; 10 fields/liver section.

a

P < 0.05 significant differences compared to naïve group.

b

P < 0.05 significant differences compared to precancerous lesion group.

c

P < 0.05 significant compared to cyanidin-3-O-glucoside-10, One-way ANOVA followed by Tukey’s test. +: Positive expression found in 1-3 fields; ++: Positive expression found in 4-6 fields; +++: Positive expression found in 7-10 field; PCL: Precancerous lesion; Cyan: Cyanidin-3-O-glucoside; GSTP: Glutathione S-transferase placental; PCNA: Proliferating cell nuclear antigen.