Table 3.

GO enrichment analysis.

GO:Term	Description	Count in gene set	p-value1
GO:0022402	cell cycle process	8 of 890	0.0000
GO:1903047	mitotic cell cycle process	6 of 564	0.0000
GO:0000280	nuclear division	5 of 268	0.0000
GO:0051726	regulation of cell cycle	7 of 1129	0.0000
GO:0051302	regulation of cell division	4 of 179	0.0001
GO:0051301	cell division	5 of 483	0.0001
GO:1901992	positive regulation of mitotic cell cycle phase transition	3 of 65	0.0003
GO:0007059	chromosome segregation	4 of 253	0.0003
GO:0007017	microtubule-based process	5 of 605	0.0003
GO:0000910	cytokinesis	3 of 71	0.0003
GO:0071897	DNA biosynthetic process	3 of 95	0.0005
GO:0006259	DNA metabolic process	5 of 773	0.0007
GO:0051782	negative regulation of cell division	2 of 16	0.0010
GO:0007051	spindle organization	3 of 123	0.0010
GO:0000819	sister chromatid segregation	3 of 123	0.0010
GO:0000226	microtubule cytoskeleton organization	4 of 393	0.0010
GO:0140014	mitotic nuclear division	3 of 136	0.0011
GO:0000075	cell cycle checkpoint	3 of 193	0.0027
GO:0006260	DNA replication	3 of 203	0.0028
GO:0007346	regulation of mitotic cell cycle	4 of 608	0.0036
GO:0019985	translesion synthesis	2 of 41	0.0042
GO:0010564	regulation of cell cycle process	4 of 684	0.0052
GO:0045840	positive regulation of mitotic nuclear division	2 of 54	0.0056
GO:0030071	regulation of mitotic metaphase/anaphase transition	2 of 49	0.0056
GO:0000281	mitotic cytokinesis	2 of 50	0.0056
GO:0033044	regulation of chromosome organization	3 of 313	0.0066
GO:0051225	spindle assembly	2 of 70	0.0076
GO:0007052	mitotic spindle organization	2 of 70	0.0076
GO:0051303	establishment of chromosome localization	2 of 72	0.0077

GO analyses were performed using STRING (https://string-db.org/). ¹Benjamini-Hochberg-corrected p-value. Only the 30 most significant GO terms were reported.

Summary of the biological processes of GO terms of the 10 target genes that showed differential relative mRNA expression in lung CSCs comparing early stages (I-II) with advanced stages (IIIA) NSCLC.