Table 2.

Network topological characteristic of top 20 nodes in PPI network.

Gene	label	Degree	Average ShortestPath Length	BetweennessCentrality	ClosenessCentrality	ClusteringCoefficient	Stress	TopologicalCoefficient
RPS2	Turquoise	304	2.796578	0.088088	0.35758	0.002084	35651276	0.011482
PPP2R1A	Turquoise	285	2.733026	0.10859	0.365895	0.001112	32731778	0.008927
CDK1	Green	277	2.606464	0.086532	0.383662	0.007953	23033244	0.008038
FBL	Turquoise	272	2.764259	0.083119	0.361761	0.003337	26783624	0.009266
PLK1	Turquoise	271	2.749593	0.087714	0.36369	0.002952	24705604	0.009257
TRIM28	Turquoise	251	2.847094	0.07047	0.351235	0.000829	35607200	0.02181
CDK4	Turquoise	215	2.763987	0.064648	0.361796	0.002478	17600494	0.009869
PRMT1	Turquoise	174	2.833786	0.051374	0.352885	0.003654	15009342	0.013589
SF3A2	Brown	156	2.933188	0.048426	0.340926	0	11812770	0.028122
ITCH	Brown	155	2.893808	0.049782	0.345565	0.000922	10898838	0.016011
ANLN	Green	149	2.937534	0.055011	0.340422	0.000998	7721342	0.020761
USP15	Brown	146	2.891092	0.04818	0.34589	0.001606	9324218	0.015811
CCNB1	Green	144	2.747691	0.02827	0.363942	0.019814	5878754	0.013833
EHMT2	Turquoise	132	2.939164	0.038808	0.340233	0	8115194	0.02823
CCNA2	Green	126	2.771863	0.026821	0.360768	0.01981	4666808	0.015196
USP9X	Brown	125	2.898968	0.034266	0.34495	0.001419	9220858	0.020271
HCFC1	Brown	120	2.885117	0.032388	0.346606	0.003641	7730212	0.018792
KIF11	Green	118	2.847366	0.039087	0.351202	0.001883	5902744	0.013225
TOP2A	Green	106	2.892178	0.020279	0.34576	0.004672	7719634	0.024587