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. 2021 Apr 7;23(6):427. doi: 10.3892/mmr.2021.12066

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Copyright: © Meng et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Figure 5. — SEC61G knockdown promotes human kidney cancer cell apoptosis. A498 and 769-P cells were transfected with siSEC61G or NC. Effect of SEC61G knockdown on (A) A498 cell apoptosis and (B) 769-P cell apoptosis. (C) Effect of SEC61G knockdown on BCL-2, Bax, Cleaved caspase-3 protein expression levels in A498 cells. (D) Effect of SEC61G knockdown on BCL-2, Bax, Cleaved caspase-3 protein expression levels in 769-P cells. Data are presented as the mean ± SD of three independent experiments. ***P<0.001 vs. NC. SEC61G, SEC61 translocon subunit-γ; si, small interfering RNA; NC, negative control.