Table 9. Number and concentration levels.
Recommended practice | Use an IQC with level close to clinical decision limits practice (e.g., infectious serology, troponin, D-Dimers, haemoglobin A1c, glucose). Cover the physiological and pathological range (if IQCs are available). Use multiple levels of IQC and at least 2 levels after calibration (12). |
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Acceptable practice | Other uses of IQC (excluding calibration verification). |
Unacceptable practice | Use only one level of IQC after calibration practice (unless recommended by the supplier). No appropriate verification over the entire measuring range. Absence of a well thought-out strategy leading to a risk of not detecting drift of clinical decision limits in the measurement ranges. |
IQC – internal quality control. |