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. 2021 Mar 31;23(3):e24602. doi: 10.2196/24602

Table 1.

Study characteristics of chronic obstructive pulmonary disease and asthma studies.

COPDa and asthma studyb Country Participants Setting Participants, mean (SD) Gender (female), n (%) Severityc CGd Intervention (weeks) Follow-up (weeks)


IGe CG
IG CG




COPD (included in the meta-analysis)

Bentley et al [45] England 25 23 Home 67.20 (11.60) 65.90 (9.40) f Home visits 8 32

Chau et al [48] China 22 18 Home 73.50 (6.10) 72.20 (6.10) 1 (3) II-IV Home visits 8

Casas et al [47] Spain and Belgium 65 90 Home and SCg 70.00 (90.00) 72.00 (90.00) 26 (16.8) I-IV UCh 4 48

Garcia et al [22] Spain 21 41 Home and SC 73.00 (6.00) 74.00 (8.00) 8 (13) UC 48

Jehn et al [50] Germany 32 30 Home and PCi 64.10 (10.90) 69.10 (9.20) 14 (23) II-IV UC+PC visits 36

Koff et al [24] United States 20 20 Home and SC 66.60 (9.10) 65.00 (8.20) 21 (53) III-IV UC 12

Nguyen et al [51] United States 19 20 Home and PC 68.00 (8.30) 70.90 (8.60) 17 (44) Home visits 24

Wang et al [54] China 55 65 Home and SC 69.30 (7.80) 71.90 (8.10) 63 (52.5) II-IV UC 24 48

Wang et al [55] China 39 39 Home and SC 63.20 (7.50) 64.40 (7.00) 23 (30) Mostly II-IV SC visits 48

Wei et al [56] China 42 45 Home and SC 65.20 (8.10) 63.90 (6.20) I-IV UC 24 48

Xin et al [57] China 114 113 Home and SC 64.20 (14.20) 64.60 (14.50) 141 (62.1) UC 48
COPD (not included in the meta-analysis)

Cameron et al [46] Australia 35 30 Home and SC 68.00 (9.90) 70.00 (6.80) I-IV UC 8 17

Haesum et al [49] Denmark 47 43 Home and PC 70.20 (9.00) 69.50 (10.10) 47 (52) I-IV UC 4 40

Sorknaes et al [52] Denmark 121 121 Home and PC 71.00 (10.00) 72.00 (9.00) I-IV PC visits 12 26

Stamenova et al [53] Canada 41 41 Home and SC 71.98 (9.52) 71.76 (7.28) 36 (44) II-IV SC visits 24

Stamenova et al [53] Canada 41 40 Home and SC 71.98 (9.52) 72.78 (9.16) 37 (46) II-IV UC 24
Asthma (included in the meta-analysis)

Cao et al [58] China 37 30 Home and SC 39.10 (14.30) 41.40 (12.00) 52 (78) SC visits 12

Ostojic et al [60] United States 8 8 Home and PC 24.80 (6.30) 24.50 (7.00) 7 (44) Mj UC 16

Türk et al [61] The Netherlands 7 10 SC 41.57 (12.54) 41.90 (8.58) 13 (77) SC visits 12 48

Türk et al [61] The Netherlands 14 10 SC 41.57 (9.73) 41.90 (8.58) 19 (79) SC visits 12 48

van der Meer et al [25] The Netherlands 101 99 Home and SC 36.00 (19.00; 50.00) 37.00 (18.00; 50.00) 139 (69.5) UC 12 36

van Gaalen et al [62] The Netherlands 47 60 Home and SC 36.00 (8.70) 37.00 (8.00) 76 (71.0) UC 48 120
Asthma (not included in the meta-analysis)

Barbanel et al [23] England 12 12 Home and SC 45.00 (17.00) 47.00 (17.00) 13 (54) UC 12

Kohler et al [59] Germany 41 41 Home and PC 49.00 (12.00) 52.00 (8.00) 32 (39) PCi visits 3

aCOPD: chronic obstructive pulmonary disease.

bStudy by Bentley et al [45] and Nguyen et al [51] were feasibility RCTs, and study by Chau et al [48] was a pilot RCT. There was 1 study including 1 intervention group and 2 control groups (study by Stamenova et al [53]). Study by Türk et al [61] included 2 intervention groups and 1 control group.

cCOPD severity was classified according to GOLD (Global Initiative for Chronic Obstructive Lung Disease) classification. Asthma severity was classified by the physician diagnosis.

dCG: control group.

eIG: intervention group.

fNot reported in the study.

gSC: secondary care.

hUC: usual care.

iPC: primary care.

jM: moderate severity.