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. 2021 Apr 1;221:108591. doi: 10.1016/j.drugalcdep.2021.108591

Table 2.

Patterns of cannabis use from 13 to 18 years and cognitive functioning at age 24 (fully adjusted models).

Non-user Late-onset occasional Early-onset occasional Early-onset regular
n = 3232 for all models Reference b (95% CI) b (95% CI) b (95% CI) Wald (df) p value
Working memory −0.10 (-0.22, 0.03) 0.12 (-0.17, 0.41) −0.62 (-0.93, -0.31) 18.56 (3) p < 0.001
Response inhibition 0.04 (-0.04, 0.11) 0.05 (-0.11, 0.22) 0.30 (0.08, 0.52) 9.24 (3) p = 0.02
Emotion recognition −0.00 (-0.01, 0.01) 0.02 (-0.00, 0.05) −0.02 (-0.05, 0.01) 4.23 (3) p = 0.24

Note. Models adjusted for socioeconomic status, working memory at age ∼11 years; head injury/ unconsciousness up to age 11 years, and alcohol use before 13 years of age; Wald tests determine whether there were differences between patterns of tobacco use and subsequent cognitive functioning; Working memory: negative d’ scores reflect poorer performance; Response inhibition: longer reaction times reflect poorer performance; Emotion recognition: negative scores reflect poorer performance.