Figure 4.

Motions of the RBD and the NTD in fully glycosylated systems and non-glycosylated systems. (A) Illustration of the NTD–RBD distance (d) and the RBD orientation angle (θ). (B) Time series of d and θ in three chains of 6VSB. d is defined by the minimum distance between the RBD (N334 to P527) and the NTD (C15 to S305). θ is defined by three points corresponding to the (i) COM of L452 and L492, (ii) COM of N334, and (iii) COM of S1030. The ranges of d and θ observed in the available PDB S protein structures are shaded by gray regions.