Table 4.
In Vitro Oxazolidinone Activity Against Rapidly Growing Mycobacteria
| Oxazolidinone MIC50, MIC90, µg/mL (No. of Isolates) |
|||
|---|---|---|---|
| Organism | Tedizolid | Linezolid | Reference |
| M. abscessus | 1, 4 (43) | 8, >32 (43) | [5] |
| 4, 8 (81) | 16, 32 (81) | [6] | |
| 2, 8 (15) | 8, 64 (15) | [7] | |
| M. bolletii | 4, 4 (5) | 32, >32 (5) | [5] |
| 2, 4 (14) | 16, 32 (14) | [7] | |
| M. massiliense | 1, 4 (82) | 8, >32 (82) | [5] |
| 2, 4 (12) | 8, 32 (12) | [6] | |
| 4, 8 (15) | 16, 32 (15) | [7] | |
| M. chelonae | 1, 2 (22) | 8, 16 (22) | [6] |
| M. mucogenicum group | 1, NA (9) | 1, NA (9) | [6] |
| M. immunogenum | 1, NA (9) | 8, NA (9) | [6] |
| M. fortuitum | 1, 2 (20) | 2, 4 (20) | [6] |
Abbreviation: MIC, minimal inhibitory concentration.