Table 1.
Baseline characteristics of patients ⩾75 years with acute BAO.
| Characteristics | All patients | Intervention | Conservative | p-value |
|---|---|---|---|---|
| (n = 182) | (n = 127) | (n = 55) | ||
| Age, median (IQR), years | 78 (76–81) | 78 (76–81) | 79 (77–81) | 0.363 |
| Sex, male, n (%) | 107 (58.8) | 79 (62.2) | 28 (50.9) | 0.155 |
| NIHSS baseline score, median (IQR) | 28 (16–34) | 28 (17–34) | 22 (14–31) | 0.025 |
| pc-ASPECTS baseline, median (IQR)a | 8 (6–9) | 8 (7–9) | 7 (6–9) | 0.062 |
| PC-CS score, median (IQR) | 4 (3–6) | 4 (4–6) | 4 (2–6) | 0.196 |
| SBP, mean (SD), mm Hg | 156 (27.4) | 152 (26.0) | 164 (28.9) | 0.008 |
| DBP, mean (SD), mm Hg | 85 (15.8) | 84 (16.0) | 89 (15.1) | 0.062 |
| Medical history, n (%) | ||||
| Hypertension | 142 (78.0) | 102 (80.3) | 40 (72.7) | 0.256 |
| Hyperlipidemia | 34 (18.7) | 21 (16.5) | 13 (23.6) | 0.259 |
| Diabetes mellitus | 36 (19.8) | 24 (18.9) | 12 (21.8) | 0.650 |
| Atrial fibrillation | 68 (37.4) | 56 (44.1) | 12 (21.8) | 0.004 |
| Cerebral infarction | 48 (26.4) | 32 (25.2) | 16 (29.1) | 0.584 |
| Intracerebral hemorrhage | 6 (3.3) | 3 (2.4) | 3 (5.5) | 0.283 |
| Coronary artery disease | 39 (21.4) | 30 (23.6) | 9 (16.4) | 0.273 |
| Heart failure | 14 (7.7) | 9 (7.1) | 5 (9.1) | 0.870 |
| Chronic bronchitis | 3 (1.6) | 2 (1.6) | 1 (1.8) | 1.000 |
| Current or ex-smoker | 34 (18.7) | 28 (22.0) | 6 (10.9) | 0.077 |
| Cause of stroke, n (%) | 0.001 | |||
| Large artery atherosclerosis | 86 (47.3) | 56 (44.1) | 30 (54.5) | |
| Cardioembolism | 80 (44.0) | 65 (51.2) | 15 (27.3) | |
| Other causes | 16 (8.8) | 6 (4.7) | 10 (18.2) | |
| Occlusion sites, n (%) | 0.032 | |||
| Distal basilar artery | 84 (46.2) | 65 (51.2) | 19 (34.5) | |
| Middle basilar artery | 61 (33.5) | 34 (26.8) | 27 (49.1) | |
| Proximal basilar artery | 18 (9.9) | 13 (10.2) | 5 (9.1) | |
| Vertebral artery-V4 | 19 (10.4) | 15 (11.8) | 4 (7.3) | |
| Intravenous thrombolysis, n (%) | 35 (19.2) | 22 (17.3) | 13 (23.6) | 0.321 |
| OTT, median (IQR), min | 239 (121–362) | 261 (151–365) | 208 (89–329) | 0.046 |
a
Data were missing for one patient in the conservative cohort.
BAO, basilar artery occlusion; DBP, diastolic blood pressure; IQR, interquartile rage; NIHSS, National Institutes of Health Stroke Scale; OTT, onset-treatment time; pc-ASPECTS, posterior circulation Alberta Stroke Program Early Computed Tomography Score; PC-CS score, posterior circulation collateral system score; SBP, systolic blood pressure.