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. 2021 Apr 12;8(1):e001627. doi: 10.1136/openhrt-2021-001627

Table 2.

Antibiotics, echocardiography and procedures

Variables Non-elderly Elderly Very elderly P value
(n=7803) (n=7874) (n=4990)
Antibiotics for more than 2 weeks
 Penicillin system 3364 (43.1%) 3177 (40.3%) 1730 (34.7%) <0.001*
 Cephem system 2489 (31.9%) 2202 (28.0%) 1356 (27.2%) <0.001*
 Carbapenem 600 (7.7%) 687 (8.7%) 458 (9.2%) 0.007*
 Aminoglycoside 2961 (37.9%) 2468 (31.3%) 1153 (23.1%) <0.001*
 Glycopeptide 1237 (15.9%) 1452 (18.4%) 783 (15.7%) <0.001*
 Daptomycin 275 (3.5%) 298 (3.8%) 130 (2.6%) 0.001*
 Linezolid 142 (1.8%) 119 (1.5%) 45 (0.9%) <0.001*
 Antifungal antibiotics 131 (1.7%) 237 (3.0%) 102 (2.0%) <0.001*
 Others 1785 (22.9%) 2119 (26.9%) 1585 (31.8%) <0.001*
Echocardiography
TTE 7263 (93.1%) 7251 (92.1%) 4556 (91.3%) 0.001*
TEE 4007 (51.4%) 3700 (47.0%) 1494 (29.9%) <0.001*
Intensive treatment within 2 days after admission
Admission to HCU 266 (3.4%) 305 (3.9%) 178 (3.6%) 0.289
Admission to ICU 1255 (16.1%) 1055 (13.4%) 347 (7.0%) <0.001*
 Inotropic therapy 1236 (15.8%) 1205 (15.3%) 500 (10.0%) <0.001*
 Ventilation Support 754 (9.7%) 674 (8.6%) 237 (4.7%) <0.001*
 CRRT 135 (1.7%) 175 (2.2%) 49 (1.0%) <0.001*
 IRRT 348 (4.5%) 498 (6.3%) 145 (2.9%) <0.001*
 PMX-DHP 36 (0.5%) 29 (0.4%) 7 (0.1%) 0.01*
Surgical treatment 2894 (37.1%) 2246 (28.5%) 465 (9.3%) <0.001*

Data are expressed as number (percentage).

*P values are significant.

CRRT, continuous renal replacement therapy; HCU, high care unit; ICU, intensive care unit; IRRT, intermittent renal replacement therapy; PMX-DHP, Polymyxin B-immobilised fibre column-direct hemoperfusion; TEE, transoesophageal echocardiography; TTE, transthoracic echocardiography.