Table 3.

Univariate and multivariate analysis to identify potential predictor in predicting regional lymph node metastasis

		Univariate analysis		Multivariate analysis
		OR (95% CI)	P Value	OR (95% CI)	P Value
Age	≤ 60	Reference 0.433 (0.137–1.376)	0.209	–	–
	>  60
Gender	Male	Reference 0.957 (0.390–2.351)	1.000	–	–
	Female
Tumor size	T1	Reference 59.933 (7.797–460.704)	0.000	Reference 15.175 (1.436–160.329)	0.024
	T2
Tumor location	Anterior/ Middle	Reference 5.395 (2.259–12.888)	0.003	Reference 6.311 (1.514–26.304)	0.011
	Posterior
rTTT*	Minimal rTTT	Reference 31.067 (10.407–111.518)	0.000	Reference 11.528 (2.483–53.530)	0.002
	Significant rTTT
PLD	> 5 mm	Reference 29.000 (6.486–129.668)	0.000	Reference 11.976 (1.981–72.413)	0.007
	≤ 5 mm
SLD	>  4 mm	Reference 3.780 (1.417–10.088)	0.006	–	–
	≤ 4 mm
Cell-differentiation	Well	Reference 1.241 (0.552–2.792)	0.681	–	–
	Moderate/ Poor

Abbreviations: OR = odds ratio, CI = confidence interval, PLD = Paralingual Distance, SLD = Sublingual Distance

^* rTTT (radiologic tumor thickness threshold) was categorized into two groups: “minimal” and “significant” rTTT, depending on how many MRI-assessed tumor thicknesses exceed their cutoff values. Minimal rTTT was defined as only one orientation of MRI thickness (either aTT, cTT or sTT) found to be greater than its defined cutoff value or no MRI thicknesses exceeding their cutoff values, whereas significant rTTT was defined as at least two orientations of MRI thickness (either aTT, cTT or sTT) exceeding their cutoff values