Skip to main content
. Author manuscript; available in PMC: 2021 Apr 15.
Published in final edited form as: Cell Rep. 2021 Mar 16;34(11):108869. doi: 10.1016/j.celrep.2021.108869

Figure 5. Cells lacking SFXN1 display metabolic flexibility.

Figure 5.

(A) Oxygen consumption rate (OCR) in intact cells. Presented are values normalized by DNA content (mean ± SEM, n = 4).

(B) Extracellular acidification rate (ECAR) in intact cells. Presented are values normalized by DNA content (mean ± SEM, n = 5).

(C) OCR in isolated mitochondria using the specified substrates (mean ± SEM, n ≥ 9 wells from at least 3 independent experiments). mal, malate; DMK, dimethyl αKG; G3P, glycerol-3-phosphate.

(D) Percent dependency on glutamine (Gln), glucose (Gluc), and fatty acid (FA) use (mean ± SEM, n = 3). *p < 0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001; unpaired Student’s t test.