Table 4:

Odds of elevated ALT and advanced fibrosis by MetS-Z, overall and by race/ethnicity.^a

	Overall	White	Black	Hispanic	Other	Mets-Z × Race Interaction p-value
Elevated ALTb
Unadjusted	1.58 [1.44, 1.72]	1.82 [1.57, 2.1]	1.15 [1.02, 1.31]	1.39 [1.21, 1.61]	1.48 [1.15, 1.91]	< 0.0001
Adjusted for age, sex, race/ethnicity, diabetes status	1.64 [1.46, 1.83]	1.87 [1.60, 2.2]	1.20 [1.05, 1.37]	1.46 [1.24, 1.72]	1.56 [1.18, 2.10]	0.0002
Elevated ALT above 97.5%tile
Unadjusted	1.49 [1.34, 1.65]	1.60 [1.40, 1.84]	1.14, [0.76, 1.70]	1.38 [1.19, 1.60]	1.91 [1.00, 3.69]	0.2122
Adjusted for age, sex, race/ethnicity, diabetes status	1.48 [1.25, 1.77]	1.62 [1.34, 1.95]	1.14 [0.80, 1.63]	1.38 [1.11, 1.73]	1.93 [1.03, 3.60]	0.0931
Fibrosis stage 3 or 4c
Unadjusted	1.96 [1.77, 2.18]	2.2 [1.78, 2.72]	1.79 [1.46, 2.18]	1.74 [1.5, 2.02]	0.36 [0.18, 0.74]	0.0001
Adjusted for age, sex, race/ethnicity, diabetes status	1.16 [1.0, 1.3]	1.24 [1.04, 1.46]	1.17 [0.98, 1.39]	1.06 [0.84, 1.34]	0.12 [0.05, 0.27]	<0.0001
Elevated NFS and Fib4 d
Unadjusted	1.29 [0.90, 1.85]	1.61 [1.41, 1.85]	1.24 [1.01, 1.52]	1.73 [1.51, 1.99]	0.36 [0.18, 0.74]	0.0006
Adjusted for age, sex, race/ethnicity, diabetes status	0.70 [0.3, 1.6]	1.08 [0.62, 1.91]	0.75 [0.35, 1.62]	1.47 [1.03, 2.10]	0.08 [0.02, 0.37]	0.0048

^a.Presented: Odds ratio [95% CI]

^b.ALT >40 in males and >31 in females [12]

^c.NASH Fibrosis Score > 0.676

^d.NASH Fibrosis Score > 0.676 and Fib4 ≥ 2.67