Table 2.
Sociodemographic and clinical characteristics by BMI trajectory groups (N = 264,230)
| Trajectory 1 (overweight-S) (n = 95,944) |
Trajectory 2 (Obese 1-S) (n = 104,616) |
Trajectory 3 (obese 2-S) (n = 50,866) |
Trajectory 4 (obese 3-S) (n = 12,804) |
|
|---|---|---|---|---|
| Patient characteristics (Sociodemographic characteristics) | ||||
| Age at start of study (mean (SD)) | 49.5 (13.2) | 49.9 (12.7) | 49.1 (12.2) | 48.8 (11.2) |
| Male gender n (%) | 37,882 (39.5) | 41,685 (39.9) | 16,652 (32.7) | 3371 (26.3) |
| Smoking | ||||
| Ex-smoker | 27,950 (29.1) | 31,763 (30.4) | 15,123 (29.7) | 3703 (28.9) |
| Light smoker (1–9 cigs/day) | 6918 (7.2) | 7071 (6.8) | 3270 (6.4) | 794 (6.2) |
| Moderate smoker (10–19 cigs/day) | 5118 (5.3) | 5214 (5.0) | 2347 (4.6) | 503 (3.9) |
| Heavy smoker (20–39 cigs/day) | 3827 (4.0) | 4470 (4.3) | 2297 (4.5) | 619 (4.8) |
| Non-smoker | 52,070 (54.3) | 55,989 (53.5) | 27,757 (54.6) | 7153 (55.9) |
| Missing | 61 (0.1) | 109 (0.1) | 72 (0.1) | 32 (0.3) |
| Alcohol consumption | ||||
| Trivial (< 1 unit/day) | 31,978 (33.3) | 35,035 (33.5) | 17,192 (33.8) | 4203 (32.8) |
| Light (1–2 units/day) | 16,405 (17.1) | 15,773 (15.1) | 6133 (12.1) | 1112 (8.7) |
| Moderate (3–6 units/day) | 9746 (10.2) | 8748 (8.4) | 3314 (6.5) | 586 (4.6) |
| Heavy (7–9 units/day) | 2883 (3.0) | 2961 (2.8) | 1076 (2.1) | 170 (1.3) |
| Very heavy (> 9 units/day) | 1621 (1.7) | 1905 (1.8) | 722 (1.4) | 129 (1.0) |
| Ex-alcohol consumption | 3086 (3.2) | 3759 (3.6) | 2174 (4.3) | 641 (5.0) |
| No alcohol consumption | 28,076 (29.3) | 33,168 (31.7) | 18,113 (35.6) | 5341 (41.7) |
| Missing | 2149 (2.2) | 3267 (3.1) | 2142 (4.2) | 622 (4.9) |
| Deprivation (IMD quintile) | ||||
| 1 (least deprived) | 10,122 (10.6) | 10,251 (9.8) | 4334 (8.5) | 827 (6.5) |
| 2 | 11,043 (11.5) | 12,124 (11.6) | 5549 (10.9) | 1242 (9.7) |
| 3 | 9644 (10.1) | 11,386 (10.9) | 5654 (11.1) | 1386 (10.8) |
| 4 | 9889 (10.3) | 12,173 (11.6) | 6412 (12.6) | 1693 (13.2) |
| 5 (most deprived) | 7528 (7.9) | 9818 (9.4) | 5799 (11.4) | 1766 (13.8) |
| Missing records | 47,718 (49.7) | 48,864 (46.7) | 23,118 (45.5) | 5890 (46.0) |
| Weight profile and clinical characteristics | ||||
| Body mass index in kg/m2 (mean (SD)) | ||||
| Baseline BMI | 28.7 (2.2) | 33.7 (2.7) | 39.9 (3.5) | 49.1 (5.7) |
| BMI at 2 years | 28.6 (2.2) | 33.7 (2.4) | 39.9 (3.2) | 49.1 (5.4) |
| BMI at 5 years | 29.2 (2.3) | 34.5 (2.4) | 40.8 (3.1) | 50.0 (5.3) |
| BMI at 8 years | 29.5 (2.5) | 34.8 (2.6) | 41.1 (3.3) | 50.1 (5.4) |
| BMI at 10 years | 29.7 (2.8) | 34.9 (3.0) | 41.1 (3.7) | 49.8 (5.7) |
| Mean BMI change over 10 years | 1.0 (3.1) | 1.2 (3.7) | 1.0 (4.6) | 0.6 (6.3) |
| Prevalence of comorbidities at baseline | ||||
| Atrial fibrillation | 671 (0.7) | 865 (0.8) | 452 (0.9) | 156 (1.2) |
| Chronic kidney disease | 771 (0.8) | 998 (1.0) | 532 (1.0) | 159 (1.2) |
| Hypertension | 15,708 (16.4) | 21,438 (20.5) | 12,009 (23.6) | 3419 (26.7) |
| Type-2 diabetes | 6384 (6.7) | 8930 (8.5) | 5609 (11.0) | 1921 (15.0) |
| Rheum arthritis/inflammatory diseases | 1674 (1.7) | 1970 (1.9) | 952 (1.9) | 261 (2.0) |