Table 3.
Results of the Spearman’s correlation between the clinically and radiologically measured response to the treatment and the difference between the preCHT and postCHT metabolites
| Response to the iCHT | Correlation with the difference between the preCHT- postCHT metabolites | |||||
|---|---|---|---|---|---|---|
| All patients | Stratified according to metabolic response | Sex stratified | ||||
| Grey | Red | Green | M | F | ||
| cT-yT |
Lip 1.3 ppm (R = -0.31) ↑ NAG (R = 0.33) ↓ |
Lip 0.9 ppm (R = -0.38) ↑ Lip 1.3 ppm (R = -0.46) ↑ |
– |
Alanine (R = 0.7) ↓ NAG (R = 0.73) ↓ |
Lip 0.9 ppm (R = -0.55) ↑ Lip 1.3 ppm (R = -0.57) ↑ Lip 5.3 ppm (R = -0.47) ↑ NAG (R = 0.41) ↓ |
– |
| cN-yN | – | – | – | – | – | – |
| Primary tumor regression [%] | – | – | – | Alanine (R = 0.77) ↓ |
LIP 0.9 ppm (R = -0.45) ↑ Lip 1.3 ppm (R = -0.40) ↑ |
– |
Legend: only statistically significant (p < 0.05, R > 0.3) values are presented. The arrows denote the increase/decrease of the particular metabolites, which is correlated with the tumor downstaging/shrinkage.