FIGURE 5.

Holistic neutrophil response to FFA2R activation and analysis of underlying pathway composition. DMR recordings of human neutrophils stimulated with increasing concentrations of C3 (A) or 4‐CMTB (B). Cell response of neutrophil pretreated for 1 h with or without G protein inhibitors (3 µg/ml PTX, 1µM FR) and stimulated with 3 mM C3 (C) or 100 µM 4‐CMTB (D). Traces are depicted as mean + sem measured in triplicates, DMR signatures are corrected for response toward vehicle addition