TABLE 1.
Characteristics of patients with brain gliomas (N = 135)
| Characteristics (N = 135) | N (%) |
|---|---|
| Median age (range) (y) a | 55.8 (22.5‐86.8) |
| Gender | |
| Men | 88 (65.2%) |
| Women | 47 (34.8%) |
| Race/ethnicity | |
| White (non‐Hispanic) | 94 (69.6%) |
| Hispanic | 18 (13.3%) |
| Asian | 10 (7.4%) |
| African American | 1 (0.7%) |
| Other/unknown | 12 (8.9%) |
| Types of brain tumors | |
| Diffuse astrocytoma (grade II) | 7 (5.2%) |
| IDH wild type | 3 (2.2%) |
| IDH mutant | 3 (2.2%) |
| NOS | 1 (0.7%) |
| Oligodendroglioma (grade II) | 10 (7.4%) |
| IDH mutant and 1p/19q‐codeleted | 8 (5.9%) |
| NOS | 2 (1.5%) |
| Anaplastic oligodendroglioma (grade III) | 4 (3.0%) |
| IDH mutant and 1p/19q‐codeleted | 2 (1.5%) |
| NOS | 2 (1.5%) |
| Anaplastic astrocytoma (grade III) | 21 (16%) |
| IDH wild type | 7 (5.2%) |
| IDH mutant | 12 (8.9%) |
| NOS | 2 (1.5%) |
| Glioblastoma multiforme (grade IV) | 93 (69%) |
| IDH wild type | 79 (59%) |
| IDH mutant | 7 (5.2%) |
| NOS | 7 (5.2%) |
Abbreviations: %cfDNA, mutant allele frequency; cfDNA, cell‐free DNA; IQR, interquartile range; NOS, not otherwise specified; VUS, variant of unknown significance.
a
Age at the time of blood draw for cfDNA analysis.