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CDX2 expression was negatively regulated by p‐FoxO4. (A‐B) GES‐1 and BGC823 cells were transfected with FoxO4 small interfering RNA (siFoxO4). With the decrease in p‐FoxO4 Ser262, the expression of CDX2 and intestinal markers increased at the protein (upper) and mRNA (lower) levels. (C) AGS cells were transfected with FoxO4 lentivirus. The absolute increase in p‐FoxO4 Ser262 could reduce the expression of CDX2 at the protein (upper) and mRNA (lower) levels
