TABLE 2.
Cox proportional hazard analyses for 30‐day mortality risk
| Model 1 ‐ unadjusted | Model 2 ‐ adjusted | Model 3 ‐ adjusted | |||
|---|---|---|---|---|---|
| Covariables | HR [95% CI] | Covariables | HR [95% CI] | Covariables | HR [95% CI] |
| Slightly prolonged PT | 1.28 [0.92–1.77] | Slightly prolonged PT | 1.13 [0.81–1.57] | Slightly prolonged PT | 1.11 [0.80–1.55] |
| Intermediately prolonged PT | 1.10 [0.78–1.54] | Intermediately prolonged PT | 0.83 [0.59–1.17] | Intermediately prolonged PT | 0.80 [0.56–1.13] |
| Extremely prolonged PT | 2.21 [1.63–2.98] | Extremely prolonged PT | 1.15 [0.83–1.59] | Extremely prolonged PT | 1.13 [0.81–1.60] |
| Age | 1.02 [1.01–1.02] | Age | 1.02 [1.01–1.02] | ||
| APACHE IV APS | 1.02 [1.02–1.03] a | Gender, male | 0.91 [0.73–1.14] | ||
| White race | 1.21 [0.82–1.79] | ||||
| APACHE IV APS | 1.02 [1.02–1.03] a | ||||
| Malignancy | 1.32 [1.03–1.69] | ||||
| Immunocompromise | 1.21 [0.93–1.57] | ||||
| Renal compromise | 0.92 [0.67–1.27] | ||||
| Lung infection | 1.38 [1.06–1.78] | ||||
| Abdominal infection | 1.34 [0.97–1.85] | ||||
| Gram negative infection | 0.92 [0.74–1.67] | ||||
| Lowest platelet count first 24 h | 0.999 [0.998–0.999] | ||||
| Fresh frozen plasma units transfused in first 24 h | 0.87 [0.74–1.01] | ||||
Abbreviations: APACHE, Acute Physiology and Chronic Health Evaluation; APS, Acute Physiology Score; CI, confidence interval; HR, hazard ratio; PT, prothrombin time.
a
Proportionality was not met for APACHE IV APS.