TABLE 1.
Longitudinal cohort characteristics
| Baseline characteristics of subjects included in longitudinal analysis | PIAMA | Asthma cohort | |
|---|---|---|---|
| Asthma | Non‐asthma | Asthma | |
| Subjects | 52 (10.7%) | 433 (89.5%) | 133 (100%) |
| Age | 8.0 (0.3) | 8.1 (0.3) | 9.8 (1.3) |
| Male | 28 (53.8%) | 206 (47.6%) | 101 (75.9%)** |
| FEV1% predicted, % | 102.0 (12.9)* | 106.8 (10.6) | 75.0 (14.1)** |
| FVC% predicted, % | 103.2 (11.3) | 104.6 (10.6) | 89.8 (12.5)** |
| FEV1/FVC% predicted, % | 98.2 (8.4)* | 101.5 (6.5) | 82.8 (10.1)** |
| Blood eosinophils (10^9/L)† | 0.47 (2.1)* | 0.30 (2.0) | 0.39 (2.4) |
| BHR | 72.3%* | 39.3% | 100%** |
| Positive skin prick test | 66.7%* | 18.1% | 99.2%** |
| Maternal atopy | 78.8%* | 64.9% | ‐ |
| Paternal atopy | 40.4% | 32.9% | ‐ |
| Low parental education | 9.6% | 7.6% | ‐ |
| Intermediate parental education | 28.8% | 31.7% | ‐ |
| High parental education | 61.5% | 60.6% | ‐ |
| Respiratory infection | 34.6% | 22.8% | ‐ |
Baseline PIAMA defined as visit at age 8. Asthma cohort baseline defined as presentation to paediatric pulmonologist. Parental education based on highest attained educational level of father or mother, low: primary school, lower vocational or lower secondary education, intermediate: vocational education or intermediate/higher secondary education, high: higher vocational education and university. Respiratory infection defined as cold or airway infection in past 3 weeks.
†
Geometric mean (geometric SD).
*
Significantly different from non‐asthma group.
**
Significantly different from PIAMA asthma group.