FIGURE 2.

Incidence trends in the Netherlands stratified by receptor subtype between 2006 and 2017 in women diagnosed with first primary invasive breast cancer. Rates were adjusted for age (European Standard Rates, ESR) by direct standardisation according to the 2013 European Standard Population 95+ and calculated per 100 000 person‐years (PY). HR + = ER+ and/or PR+, HR− = ER− and PR−. Information on ER/PR and HER2‐status was routinely collected by the Dutch cancer registry since 2005 and 2006, respectively. Note the different scaling in A