Search	Query	Items identified
#19	Search: ”english”[Language] AND #18 Sort by: Most Recent	4,751
#18	Search: #17 AND #14 Sort by: Most Recent	5,231
#17	Search: #16 OR #15 Sort by: Most Recent	3,731,983
#16	Search: systematic[sb] OR meta‐analysis[pt] OR meta‐analysis as topic[Mesh] OR meta‐analysis[Mesh] OR meta analy*[tw] OR metanaly*[tw] OR metaanaly*[tw] OR met analy*[tw] OR integrative research[tiab] OR integrative review*[tiab] OR integrative overview*[tiab] OR research integration*[tiab] OR research overview*[tiab] OR collaborative review*[tiab] OR collaborative overview*[tiab] OR systematic review*[tiab] OR comparative efficacy[tiab] OR comparative effectiveness[tiab] OR outcomes research[tiab] OR indirect comparison*[tiab] OR Embase*[tiab] OR Cinahl*[tiab] OR systematic overview*[tiab] OR methodological overview*[tiab] OR methodologic overview*[tiab] OR methodological review*[tiab] OR methodologic review*[tiab] OR quantitative review*[tiab] OR quantitative overview*[tiab] OR quantitative synthes*[tiab] OR pooled analy*[tiab] OR Cochrane[tiab] OR Medline[tiab] OR Pubmed[tiab] OR Medlars[tiab] OR handsearch*[tiab] OR hand search*[tiab] OR meta‐regression*[tiab] OR metaregression*[tiab] OR data synthes*[tiab] OR data extraction[tiab] OR data abstraction*[tiab] OR mantel haenszel[tiab] OR peto[tiab] OR der‐simonian[tiab] OR dersimonian[tiab] OR fixed effect*[tiab] OR “Cochrane Database Syst Rev”[Journal:__jrid21711] Sort by: Most Recent	421,144
#15	Search: ”clinical trial”[pt] OR “Random Allocation”[Mesh] OR randomized[tiab] OR randomised[tiab] OR placebo[tiab] OR randomly[tiab] OR trial[tiab] OR groups[tiab] OR (group 1[tiab] AND group 2[tiab]) OR “Clinical Trials as Topic”[Mesh] OR “Double‐Blind Method”[Mesh] OR “Single‐Blind Method”[Mesh] OR ((singl*[tiab] OR doubl*[tiab] OR trebl*[tiab] OR tripl*[tiab]) AND (mask*[tiab] OR blind*[tiab] OR dumm*[tiab])) OR “Cross‐Over Studies”[Mesh] OR ((crossover[tiab] OR “cross over”[tiab]) AND (study[tiab] OR studies[tiab] OR design*[tiab] OR method*[tiab] OR procedure[tiab] OR comparison[tiab])) Sort by: Most Recent	3,468,659
#14	Search: #12 NOT #13 Sort by: Most Recent	16,416
#13	Search: (rat[ti] OR rats[ti] OR mouse[ti] OR mice[ti] OR swine[ti] OR porcine[ti] OR murine[ti] OR sheep[ti] OR lambs[ti] OR pigs[ti] OR piglets[ti] OR rabbit[ti] OR rabbits[ti] OR cat[ti] OR cats[ti] OR dog[ti] OR dogs[ti] OR cattle[ti] OR bovine[ti] OR monkey[ti] OR monkeys[ti] OR trout[ti] OR marmoset*[ti]) Sort by: Most Recent	2,009,802
#12	Search: #10 NOT #11 Sort by: Most Recent	16,693
#11	Search: (“Animals”[Mesh] NOT (“Animals”[Mesh] AND “Humans”[Mesh])) Sort by: Most Recent	4,709,914
#10	Search: #3 OR #8 OR #9 Sort by: Most Recent	21,965
#9	Search: ((“Magnesium”[Mesh] OR Magnesium[tiab]) AND (“Dietary Supplements”[Mesh:noexp] OR “Food, Fortified”[Mesh] OR “Diet”[Mesh:NoExp] OR diet*[tiab] OR intak*[tiab] OR supplement*[tiab] OR therap*[tiab])) OR “Mg supplement*”[tiab] OR “Mg fortified”[tiab] OR “Magnesium/therapeutic use”[Mesh] Sort by: Most Recent	19,040
#8	Search: ((“Magnesium”[Majr] OR magnesium[ti]) AND (“Drug‐Related Side Effects and Adverse Reactions”[Mesh] OR “Poisoning”[Mesh] OR “Drug Hypersensitivity”[Mesh] OR “Drug Overdose”[Mesh] OR “Contraindications”[Mesh] OR “Risk”[Mesh] OR “Risk Factors”[Mesh] OR “Risk Assessment”[Mesh:NoExp] OR “Safety”[Mesh:NoExp] OR “Patient Safety”[Mesh] OR “Food Safety”[Mesh] OR adverse[tiab] OR contraindication*[tiab] OR “contra indication*”[tiab] OR safe[tiab] OR safety[tiab] OR risk assessment*[tiab] OR risk factor*[tiab] OR ((undesirable[tiab] OR harm*[tiab] OR serious[tiab] OR negative[tiab] OR side[tiab] OR unwanted[tiab] OR untoward[tiab]) AND (effect*[tiab] OR reaction*[tiab] OR event*[tiab] OR interaction*[tiab] OR outcome*[tiab] OR response*[tiab] OR sequala*[tiab] OR sequela*[tiab])))) OR (“magnesium/adverse effects”[MeSH Terms] OR “magnesium/poisoning”[MeSH Terms] OR “magnesium/toxicity”[MeSH Terms]) Sort by: Most Recent	3,954
#7	Search: ”magnesium/adverse effects”[MeSH Terms] OR “magnesium/poisoning”[MeSH Terms] OR “magnesium/toxicity”[MeSH Terms] Sort by: Most Recent	580
#6	Search: (“Magnesium”[Majr] OR magnesium[ti]) AND (“Drug‐Related Side Effects and Adverse Reactions”[Mesh] OR “Poisoning”[Mesh] OR “Drug Hypersensitivity”[Mesh] OR “Drug Overdose”[Mesh] OR “Contraindications”[Mesh] OR “Risk”[Mesh] OR “Risk Factors”[Mesh] OR “Risk Assessment”[Mesh:NoExp] OR “Safety”[Mesh:NoExp] OR “Patient Safety”[Mesh] OR “Food Safety”[Mesh] OR adverse[tiab] OR contraindication*[tiab] OR “contra indication*”[tiab] OR safe[tiab] OR safety[tiab] OR risk assessment*[tiab] OR risk factor*[tiab] OR ((undesirable[tiab] OR harm*[tiab] OR serious[tiab] OR negative[tiab] OR side[tiab] OR unwanted[tiab] OR untoward[tiab]) AND (effect*[tiab] OR reaction*[tiab] OR event*[tiab] OR interaction*[tiab] OR outcome*[tiab] OR response*[tiab] OR sequala*[tiab] OR sequela*[tiab]))) Sort by: Most Recent	3,497
#5	Search: ”Drug‐Related Side Effects and Adverse Reactions”[Mesh] OR “Poisoning”[Mesh] OR “Drug Hypersensitivity”[Mesh] OR “Drug Overdose”[Mesh] OR “Contraindications”[Mesh] OR “Risk”[Mesh] OR “Risk Factors”[Mesh] OR “Risk Assessment”[Mesh:NoExp] OR “Safety”[Mesh:NoExp] OR “Patient Safety”[Mesh] OR “Food Safety”[Mesh] OR adverse[tiab] OR contraindication*[tiab] OR “contra indication*”[tiab] OR safe[tiab] OR safety[tiab] OR risk assessment*[tiab] OR risk factor*[tiab] OR ((undesirable[tiab] OR harm*[tiab] OR serious[tiab] OR negative[tiab] OR side[tiab] OR unwanted[tiab] OR untoward[tiab]) AND (effect*[tiab] OR reaction*[tiab] OR event*[tiab] OR interaction*[tiab] OR outcome*[tiab] OR response*[tiab] OR sequala*[tiab] OR sequela*[tiab])) Sort by: Most Recent	3,758,191
#4	Search: ”Magnesium”[Majr] OR magnesium[ti] Sort by: Most Recent	34,053
#3	Search: (“Magnesium”[Mesh] OR magnesium[tiab]) AND (“Diarrhea”[Mesh] OR diarrhe*[tiab] OR diarrho*[tiab] OR dysenter*[tiab]OR “Feces”[Mesh] OR feces[tiab] OR fecal[tiab] OR faec*[tiab] OR laxative[tiab] OR stool*[tiab] OR osmotic effect*[tiab] OR tolerab*[tiab]) Sort by: Most Recent	1,978
#2	Search: ”Diarrhea”[Mesh] OR diarrhe*[tiab] OR diarrho*[tiab] OR dysenter*[tiab]OR “Feces”[Mesh] OR feces[tiab] OR fecal[tiab] OR faec*[tiab] OR laxative[tiab] OR stool*[tiab] OR osmotic effect*[tiab] OR tolerab*[tiab] Sort by: Most Recent	370,900
#1	Search: ”Magnesium”[Mesh] OR magnesium[tiab] Sort by: Most Recent	101,094