TABLE 3.
Rates of pCR and Ki‐67 response in patients with ECR in the MRI group and in the US group
| pCR | MRI subgroup (N = 226) | US subgroup (N = 401) | Ki‐67 response | MRI subgroup (N = 226) | US subgroup (N = 401) | ||||
|---|---|---|---|---|---|---|---|---|---|
| ECR | No ECR | ECR | No ECR | ECR | No ECR | ECR | No ECR | ||
| Overall | |||||||||
| pCR a | 61 | 22 | 71 | 66 | Ki‐67 response a | 67 | 43 | 88 | 119 |
| (42.96) | (26.19) | (46.10) | (26.72) | (47.18) | (51.19) | (57.14) | (48.18) | ||
| No pCR a | 78 | 61 | 80 | 177 | No Ki‐67 response a | 36 | 31 | 29 | 91 |
| (54.93) | (72.62) | (51.95) | (71.66) | (25.35) | (36.90) | (18.83) | (36.84) | ||
| Missing a | 3 | 1 | 3 | 4 | Missing a | 39 | 10 | 37 | 37 |
| (2.11) | (1.19) | (1.95) | (1.62) | (27.46) | (11.90) | (24.03) | (14.98) | ||
| Total b | 142 | 84 | 154 | 247 | Total b | 142 | 84 | 154 | 247 |
| (62.83) | (37.17) | (38.40) | (61.60) | (62.83) | (37.17) | (38.40) | (61.60) | ||
| HR+/HER2+ | |||||||||
| pCR a | 21 | 13 | 38 | 40 | Ki‐67 response a | 30 | 28 | 63 | 82 |
| (40.38) | (29.55) | (36.54) | (25.97) | (57.69) | (63.64) | (60.58) | (53.25) | ||
| No pCR a | 29 | 31 | 64 | 113 | No Ki‐67 response a | 8 | 14 | 21 | 53 |
| (55.77) | (70.45) | (61.54) | (73.38) | (15.38) | (31.82) | (20.19) | (34.42) | ||
| Missing a | 2 | 0 | 2 | 1 | Missing a | 14 | 2 | 20 | 19 |
| (3.85) | — | (1.92) | (0.65) | (26.92) | (4.55) | (19.23) | (12.34) | ||
| Total b | 52 | 44 | 104 | 154 | Total b | 52 | 44 | 104 | 154 |
| (54.17) | (45.83) | (40.31) | (59.69) | (54.17) | (45.83) | (40.31) | (59.69) | ||
| HR−/HER2− | |||||||||
| pCR a | 24 | 5 | 13 | 17 | Ki‐67 response a | 28 | 11 | 11 | 31 |
| (40.00) | (18.52) | (61.90) | (23.61) | (46.67) | (40.74) | (52.38) | (43.06) | ||
| No pCR a | 35 | 21 | 7 | 52 | No Ki‐67 response a | 22 | 13 | 5 | 34 |
| (58.33) | (77.78) | (33.33) | (72.22) | (36.67) | (48.15) | (23.81) | (47.22) | ||
| Missing a | 1 | 1 | 1 | 3 | Missing a | 10 | 3 | 5 | 7 |
| (1.67) | (3.70) | (4.76) | (4.17) | (16.67) | (11.11) | (23.81) | (9.72) | ||
| Total b | 60 | 27 | 21 | 72 | Total b | 60 | 27 | 21 | 72 |
| (68.97) | (31.03) | (22.58) | (77.42) | (68.97) | (31.03) | (22.58) | (77.42) | ||
| HR−/HER2+ | |||||||||
| pCR a | 16 | 4 | 20 | 9 | Ki‐67 response a | 9 | 4 | 14 | 6 |
| (53.33) | (30.77) | (68.97) | (42.86) | (30.00) | (30.77) | (48.28) | (28.57) | ||
| No pCR a | 14 | 9 | 9 | 12 | No Ki‐67 response a | 6 | 4 | 3 | 4 |
| (46.67) | (69.23) | (31.03) | (57.14) | (20.00) | (30.77) | (10.34) | (19.05) | ||
| Missing a | 0 | 0 | 0 | 0 | Missing a | 15 | 5 | 12 | 11 |
| — | — | — | — | (50.00) | (38.46) | (41.38) | (52.38) | ||
| Total b | 30 | 13 | 29 | 21 | Total b | 30 | 13 | 29 | 21 |
| (69.77) | (30.23) | (58.00) | (42.00) | (69.77) | (30.23) | (58.00) | (42.00) | ||
Abbreviations: ECR, early clinical response; MRI, magnetic resonance imaging; pCR, pathological complete response; US, ultrasound.
a
Rates of pCR, no pCR and patients with missing data among the patients with and without imaging response.
b
Share of patients with and without imaging response.